Synthesis, characterization, and biological activity assessment of new metal complexes of Schiff bases produced from benzoin

Abstract

By the reaction of Benzoin with melamine and Benzoin with 5-aminosalysilc acid a new Schiff base is obtained the reaction of the legends with Mn++, Zn++, and Ag + salts leads to the complexes [M (L)2 ] X at PH=7-6, and [M (L)2 ] at PH=9-10, L= BMA, BMS M= Mn++ Zn++ and Ag +, Several chemical and physical measurements, such as melting point, molar conductivity, and magnetic properties, as well as FT-IR spectroscopy, UV-VIS spectroscopy element analysis (C.H.N.), and (1 H-NMR)spectroscopy, and GC-MASS. was used to identify the produced ligands and complex structures, the complexes of Mn++, and Znand ++ give hexacoordinated complexes having the shape octane al but Ag+ gives tetracoordinate complexes. having shape tetrahedral. then they were screened for biological activity using agar plate diffusion technique against Gram(+) (Staphylococcus aureus bacteria, pseudomonas aeruginosa bacteria) and Gram(−) (Escherichia coli bacteria, Klebsiella pneumonia bacteria) When compared to streptomycin and trimethoprim drug, all these ligands and their complexes show good antimicrobial effectualness.

Keywords

• Schiff Bases
• Zn
• Mn
• Ag Complexes
• Benzoin
• Biological Activities