Emerging Infectious Diseases (Aug 2017)

Serologic Evidence of Powassan Virus Infection in Patients with Suspected Lyme Disease

  • Holly M. Frost,
  • Anna M. Schotthoefer,
  • Angela M. Thomm,
  • Alan P. Dupuis,
  • Sue C. Kehl,
  • Laura D. Kramer,
  • Thomas R. Fritsche,
  • Yvette A. Harrington,
  • Konstance K. Knox

DOI
https://doi.org/10.3201/eid2308.161971
Journal volume & issue
Vol. 23, no. 8
pp. 1384 – 1388

Abstract

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Powassan virus (POWV) lineage II is an emerging tickborne flavivirus with an unknown seroprevalence in humans. In a Lyme disease–endemic area, we examined the seroreactivity to POWV in 2 patient cohorts and described the clinical features of the POWV-seroreactive patients. POWV disease might be less neuroinvasive than previously thought.

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