225 Optimal-affinity MAGE-A1-specific T cell receptors (TCRs) generated using the humanized TCR-transgenic mouse platform HuTCR are superior to human donor-derived TCRs

• Matthias Leisegang,
• Thomas Blankenstein,
• Vivian Scheuplein,
• Elisa Kieback,
• Matthias Obenaus,
• Ioannis Gavvovidis

Affiliations

Matthias Leisegang

Aff2 grid.211011.20000000119425154Max Delbrück Center for Molecular MedicineHelmholtz Association Berlin Germany

Thomas Blankenstein

1st Department of Obstetrics and Gynaecology, Ludwig-Maximilians-University Munich; and

Vivian Scheuplein

1T-knife Therapeutics Inc., Berlin, Germany

Elisa Kieback

1T-knife Therapeutics Inc., Berlin, Germany

Matthias Obenaus

3Charite University Hospital, Berlin, Germany

Ioannis Gavvovidis

1T-knife GmbH, Berlin, Germany