Антибиотики и Химиотерапия (May 2020)
On Biofilms of Streptomycetes. II. Use in Biotechnology
Abstract
Streptomycetes or mycelial microorganisms are able to form biofilms under the natural, industrial and clinical conditions. The controlled use of biofilms in various industrial processes is much more efficient vs. the cultivation of plankton suspended cells. Optimization of biotechnological processes with the use of streptomycete biofilms is advisable in production of lactic acid and detoxication of the liquor in pyrolysis of plant biomass. Streptomycete biofilms are used in water purification systems. It is recommended to use biofilms for detoxication of wastes and bioremediation of soils contaminated with hard metals. The use of biofilms of streptomycetes producing biologically active substances is of special interest. High yields of antibiotics and actinomycin D in particular was observed with cultivation of antibioc-producing streptomycetes as biofilms in bioreactors of unique design.
