Nature Communications (Jul 2019)

Landscape of transcriptomic interactions between breast cancer and its microenvironment

  • Natalie S. Fox,
  • Syed Haider,
  • Adrian L. Harris,
  • Paul C. Boutros

DOI
https://doi.org/10.1038/s41467-019-10929-z
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 13

Abstract

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The transcriptomic profile of tumour-adjacent cells provides important information about tumour context but its clinical utility is unclear. Here, in breast cancer, Fox et al. show that the mRNA abundances of tumour and tumour-adjacent cells hold prognostic information.