Molecules (Mar 2000)

Enantioselective Addition of Grignard Reagents to Aldehydes

  • Norma Nudelman,
  • Hernan Schulz,
  • Pablo Englebienne

DOI
https://doi.org/10.3390/50300598
Journal volume & issue
Vol. 5, no. 3
pp. 598 – 599

Abstract

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The addition of Grignard reagents to aldehydes in the presence of chiral aminoalcohols shows a moderate enantioselectivity. The study carried out with a series of ligands allows the correlation between the structural characteristics and their reactivity.

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