In vitro evaluation of 2-pyrazoline derivatives as DPP-4 inhibitors

Temel Halide Edip; Altıntop Mehlika Dilek; Sever Belgin; Özdemir Ahmet; Akalın Çiftçi Gülşen

doi:10.1515/tjb-2022-0161

Türk Biyokimya Dergisi (Nov 2022)

In vitro evaluation of 2-pyrazoline derivatives as DPP-4 inhibitors

Temel Halide Edip,
Altıntop Mehlika Dilek,
Sever Belgin,
Özdemir Ahmet,
Akalın Çiftçi Gülşen

Affiliations

Temel Halide Edip: Department of Biochemistry, Faculty of Pharmacy, Anadolu University,Eskişehir, Türkiye
Altıntop Mehlika Dilek: Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University,Eskişehir, Türkiye
Sever Belgin: Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University,Eskişehir, Türkiye
Özdemir Ahmet: Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University,Eskişehir, Türkiye
Akalın Çiftçi Gülşen: Department of Biochemistry, Faculty of Pharmacy, Anadolu University,Eskişehir, Türkiye

DOI: https://doi.org/10.1515/tjb-2022-0161
Journal volume & issue: Vol. 48, no. 1
pp. 104 – 109

Abstract

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In this study, the synthesis of three pyrazoline derivatives and the evaluation of their inhibitory effects on dipeptidyl peptidase (DPP-4) were aimed.

Published in Türk Biyokimya Dergisi

ISSN: 1303-829X (Online)
Publisher: De Gruyter
Country of publisher: Germany
LCC subjects: Science: Chemistry: Organic chemistry: Biochemistry
Website: https://www.degruyter.com/journal/key/tjb/html

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