Breast Cancer: Basic and Clinical Research (Mar 2024)

Tissue Engineering Scaffolds Loaded With a Variety of Plant Extracts: Novel Model in Breast Cancer Therapy

  • Reyhaneh Azhari Rad,
  • Yasaman Naghdi,
  • Mobina Majidi Jamalabadi,
  • Sima Masoumi,
  • Leila Rezakhani,
  • Morteza Alizadeh

DOI
https://doi.org/10.1177/11782234241236358
Journal volume & issue
Vol. 18

Abstract

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Despite recent improvements in detecting and managing breast cancer (BC), it continues to be a major worldwide health concern that annually affects millions of people. Exploring the anti-BC potentials of natural compounds has received a lot of scientific attention due to their multi-target mode of action and good safety profiles because of these unmet needs. Drugs made from herbs are secure and have a lot fewer negative effects than those made from synthetic materials. Early stage patients benefit from breast-conserving surgery, but the risk of local recurrence remains, necessitating implanted scaffolds. These scaffolds provide residual cancer cell killing and tailored drug delivery. This review looks at plant extract–infused tissue engineering scaffolds, which provide a novel approach to treating BC. By offering patient individualized, safer treatments, these scaffolds could completely change how BC is treated.