Axially Coordinated Gold Nanoclusters Tailoring Fe–N–C Nanozymes for Enhanced Oxidase‐Like Specificity and Activity

Yameng Xie; Fuli Sun; Kuan Chang; Guang Li; Zhijia Song; Jiayu Huang; Xiqing Cheng; Guilin Zhuang; Qin Kuang

doi:10.1002/advs.202306911

Advanced Science (Mar 2024)

Axially Coordinated Gold Nanoclusters Tailoring Fe–N–C Nanozymes for Enhanced Oxidase‐Like Specificity and Activity

Yameng Xie,
Fuli Sun,
Kuan Chang,
Guang Li,
Zhijia Song,
Jiayu Huang,
Xiqing Cheng,
Guilin Zhuang,
Qin Kuang

Affiliations

Yameng Xie: State Key Laboratory of Physical Chemistry of Solid Surfaces, Collaborative Innovation Center of Chemistry for Energy Materials, Department of Chemistry, College of Chemistry and Chemical Engineering Xiamen University Xiamen 361005 China
Fuli Sun: College of Chemical Engineering Zhejiang University of Technology Hangzhou 310032 China
Kuan Chang: State Key Laboratory of Physical Chemistry of Solid Surfaces, Collaborative Innovation Center of Chemistry for Energy Materials, Department of Chemistry, College of Chemistry and Chemical Engineering Xiamen University Xiamen 361005 China
Guang Li: State Key Laboratory of Physical Chemistry of Solid Surfaces, Collaborative Innovation Center of Chemistry for Energy Materials, Department of Chemistry, College of Chemistry and Chemical Engineering Xiamen University Xiamen 361005 China
Zhijia Song: State Key Laboratory of Physical Chemistry of Solid Surfaces, Collaborative Innovation Center of Chemistry for Energy Materials, Department of Chemistry, College of Chemistry and Chemical Engineering Xiamen University Xiamen 361005 China
Jiayu Huang: State Key Laboratory of Physical Chemistry of Solid Surfaces, Collaborative Innovation Center of Chemistry for Energy Materials, Department of Chemistry, College of Chemistry and Chemical Engineering Xiamen University Xiamen 361005 China
Xiqing Cheng: School of Chemical and Environmental Engineering Shanghai Institute of Technology Shanghai 201418 China
Guilin Zhuang: College of Chemical Engineering Zhejiang University of Technology Hangzhou 310032 China
Qin Kuang: State Key Laboratory of Physical Chemistry of Solid Surfaces, Collaborative Innovation Center of Chemistry for Energy Materials, Department of Chemistry, College of Chemistry and Chemical Engineering Xiamen University Xiamen 361005 China

DOI: https://doi.org/10.1002/advs.202306911
Journal volume & issue: Vol. 11, no. 11
pp. n/a – n/a

Abstract

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Abstract Metal–organic frameworks (MOF) derived nitrogen‐doped carbon‐supported monodisperse Fe (Fe–N–C) catalysts are intensively studied, but great challenges remain in understanding the relationship between the coordination structure and the performance of Fe–N–C nanozymes. Herein, a novel nanocluster ligand‐bridging strategy is proposed for constructing Fe‐S1N4 structures with axially coordinated S and Au nanoclusters on ZIF‐8 derived Fe–N–C (labeled Aux/Fe‐S1N4‐C). The axial Au nanoclusters facilitate electron transfer to Fe active sites, utilizing the bridging ligand S as a medium, thereby enhancing the oxygen adsorption capacity of composite nanozymes. Compared to Fe‐N‐C, Aux/Fe‐S1N4‐C exhibits high oxidase‐like specificity and activity, and holds great potential for detecting acetylcholinesterase activity with a detection limit of 5.1 µU mL−1, surpassing most reported nanozymes.

Published in Advanced Science

ISSN: 2198-3844 (Online)
Publisher: Wiley
Country of publisher: Germany
LCC subjects: Science
Website: https://onlinelibrary.wiley.com/journal/21983844

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