Delayed early developmental trajectories of white matter tracts of functional pathways in preterm-born infants: Longitudinal diffusion tensor imaging data
Linda Chang,
Kentaro Akazawa,
Robyn Yamakawa,
Sara Hayama,
Steven Buchthal,
Daniel Alicata,
Tamara Andres,
Deborrah Castillo,
Kumiko Oishi,
Jon Skranes,
Thomas Ernst,
Kenichi Oishi
Affiliations
Linda Chang
Department of Medicine, School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA
Kentaro Akazawa
Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Robyn Yamakawa
Department of Medicine, School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA
Sara Hayama
Department of Medicine, School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA
Steven Buchthal
Department of Medicine, School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA
Daniel Alicata
Department of Medicine, School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA
Tamara Andres
Department of Medicine, School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA
Deborrah Castillo
Department of Medicine, School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA
Kumiko Oishi
Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA
Jon Skranes
Department of Laboratory Medicine, Children׳s and Women׳s Health, Norwegian University of Science and Technology, Trondheim, Norway
Thomas Ernst
Department of Medicine, School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA
Kenichi Oishi
Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Corresponding author at: The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, 208 Traylor Building, 720 Rutland Avenue, Baltimore, MD 21205, USA.
Probabilistic maps of white matter pathways related to motor, somatosensory, auditory, visual, and limbic functions, and major white matter tracts (the corpus callosum, the inferior fronto-occipital fasciculus, and the middle cerebellar peduncle) were applied to evaluate the developmental trajectories of these tracts, using longitudinal diffusion tensor imaging (DTI) obtained in term-born and preterm-born healthy infants. Nineteen term-born and 30 preterm-born infants completed MR scans at three time points: Time-point 1, 41.6±2.7 postmenstrual weeks; Time-point 2, 46.0±2.9 postmenstrual weeks; and Time-point 3, 50.8±3.7 postmenstrual weeks. The DTI-derived scalar values (fractional anisotropy, eigenvalues, and radial diffusivity) of the three time points are available in this Data article. Keywords: Term, Preterm, Infant, Diffusion tensor imaging, Atlas
