Feeling Stressed under the Sun? RPA1 Acetylation to the Rescue
Debabrata Chakravarti,
Tapas K. Hazra
Affiliations
Debabrata Chakravarti
Department of Obstetrics and Gynecology and Department of Pharmacology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
Tapas K. Hazra
Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, USA
Nucleotide excision repair (NER) requires replication protein A (RPA), among others, to respond to DNA damaging agents. In this issue of Cell Reports, He et al. (2017) and Zhao et al. (2017) show acetylation of RPA1 regulates the UV-induced DNA damage response.
