EGFR signalling is critical for maintaining the superficial layer of articular cartilage and preventing osteoarthritis progression

• Haoruo Jia,
• Xiaoyuan Ma,
• Basak Doyran,
• Wei Tong,
• Zeyang Sun,
• Zhaochun Yang,
• Xianrong Zhang,
• Abhishek Chandra,
• James Wang,
• Lin Han,
• Motomi Enomoto-Iwamoto,
• Ling Qin

Affiliations

Haoruo Jia

Department of Orthopaedic Surgery, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, USA

Xiaoyuan Ma

Department of Orthopaedic Surgery, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, USA

Basak Doyran

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, Pennsylvania, 19104, USA

Wei Tong

Department of Orthopaedic Surgery, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, USA

Zeyang Sun

School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, USA

Zhaochun Yang

Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pennsylvania, 15213, USA

Xianrong Zhang

Department of Physiology, School of Basic Medical Sciences, Wuhan University, Wuhan, China

Abhishek Chandra

Department of Orthopaedic Surgery, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, USA

James Wang

Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pennsylvania, 15213, USA

Lin Han

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, Pennsylvania, 19104, USA

Motomi Enomoto-Iwamoto

Department of Orthopaedic Surgery, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, USA

Ling Qin

Department of Orthopaedic Surgery, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, USA