Cancer Management and Research (Oct 2021)

Pathology Behind Constant Watery Vaginal Discharge: A Rare Case of Uterine Cervical Minimal Deviation Adenocarcinoma

  • Xie Y,
  • Zhou Q,
  • Chen L,
  • Sui L

Journal volume & issue
Vol. Volume 13
pp. 7929 – 7935


Read online

Yu Xie,* Qi Zhou,* Limei Chen, Long Sui Cervical Diseases Diagnosis and Treatment Center, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Long Sui; Limei Chen Tel +86-021-33189900Fax +86-021-63450900Email [email protected]; [email protected]: Minimal deviation adenocarcinoma (MDA) of uterine cervix is a rare malignant disease with rather poorer prognosis partially due to the early misdiagnosis. Hence, better understanding of early-stage symptoms is critical. We report a case of a 39-year-old woman came to hospital with a chief complaint of “a watery vaginal discharge for 9 months”. She was further diagnosed as having uterine cervical minimal deviation adenocarcinoma in cervical LEEP specimen and MDA stage IIIC1 (FIGO 2018 staging-after correction) in post-hysterectomy histopathology. Currently, the definitive treatment is hysterectomy with adjuvant therapy based on staging. This article gives concise symptoms, history, and images of MDA colposcopy finding and histopathology, through the whole process of diagnosis and treatment for future clinical reference.Keywords: LEEP, vaginal discharge, minimal deviation adenocarcinoma, hysterectomy