Microbiome-mediated fructose depletion restricts murine gut colonization by vancomycin-resistant Enterococcus

Abstract

Vancomycin-resistant Enterococcus (VRE) represents a major threat for patients’ health. Here, using a mouse model, the authors show that specific commensals restrict VRE gut colonization through depletion of fructose, a nutrient source that boosts VRE growth in vivo.