The bHLH-zip transcription factor SREBP regulates triterpenoid and lipid metabolisms in the medicinal fungus Ganoderma lingzhi

Yong-Nan Liu; Feng-Yuan Wu; Ren-Yuan Tian; Yi-Xin Shi; Zi-Qi Xu; Ji-Ye Liu; Jia Huang; Fei-Fei Xue; Bi-Yang Liu; Gao-Qiang Liu

doi:10.1038/s42003-022-04154-6

Communications Biology (Jan 2023)

The bHLH-zip transcription factor SREBP regulates triterpenoid and lipid metabolisms in the medicinal fungus Ganoderma lingzhi

Yong-Nan Liu,
Feng-Yuan Wu,
Ren-Yuan Tian,
Yi-Xin Shi,
Zi-Qi Xu,
Ji-Ye Liu,
Jia Huang,
Fei-Fei Xue,
Bi-Yang Liu,
Gao-Qiang Liu

Affiliations

Yong-Nan Liu: Hunan Provincial Key Laboratory of Forestry Biotechnology, Central South University of Forestry & Technology
Feng-Yuan Wu: Hunan Provincial Key Laboratory of Forestry Biotechnology, Central South University of Forestry & Technology
Ren-Yuan Tian: Hunan Provincial Key Laboratory of Forestry Biotechnology, Central South University of Forestry & Technology
Yi-Xin Shi: Hunan Provincial Key Laboratory of Forestry Biotechnology, Central South University of Forestry & Technology
Zi-Qi Xu: Hunan Provincial Key Laboratory of Forestry Biotechnology, Central South University of Forestry & Technology
Ji-Ye Liu: Hunan Provincial Key Laboratory of Forestry Biotechnology, Central South University of Forestry & Technology
Jia Huang: Hunan Provincial Key Laboratory of Forestry Biotechnology, Central South University of Forestry & Technology
Fei-Fei Xue: Hunan Provincial Key Laboratory of Forestry Biotechnology, Central South University of Forestry & Technology
Bi-Yang Liu: Hunan Provincial Key Laboratory of Forestry Biotechnology, Central South University of Forestry & Technology
Gao-Qiang Liu: Hunan Provincial Key Laboratory of Forestry Biotechnology, Central South University of Forestry & Technology

DOI: https://doi.org/10.1038/s42003-022-04154-6
Journal volume & issue: Vol. 6, no. 1
pp. 1 – 13

Abstract

Read online

An integration of genomic, DAP-seq, RNA-seq, metabolomic and genetic approaches identifies SREBP as a key transcription factor regulating triterpenoid and lipid metabolisms in the medicinal fungus Ganoderma lingzhi.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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