Frontiers in Oncology (Nov 2021)

Deep-Learning-Based Natural Language Processing of Serial Free-Text Radiological Reports for Predicting Rectal Cancer Patient Survival

  • Sunkyu Kim,
  • Choong-kun Lee,
  • Choong-kun Lee,
  • Yonghwa Choi,
  • Eun Sil Baek,
  • Jeong Eun Choi,
  • Joon Seok Lim,
  • Jaewoo Kang,
  • Sang Joon Shin,
  • Sang Joon Shin

DOI
https://doi.org/10.3389/fonc.2021.747250
Journal volume & issue
Vol. 11

Abstract

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Most electronic medical records, such as free-text radiological reports, are unstructured; however, the methodological approaches to analyzing these accumulating unstructured records are limited. This article proposes a deep-transfer-learning-based natural language processing model that analyzes serial magnetic resonance imaging reports of rectal cancer patients and predicts their overall survival. To evaluate the model, a retrospective cohort study of 4,338 rectal cancer patients was conducted. The experimental results revealed that the proposed model utilizing pre-trained clinical linguistic knowledge could predict the overall survival of patients without any structured information and was superior to the carcinoembryonic antigen in predicting survival. The deep-transfer-learning model using free-text radiological reports can predict the survival of patients with rectal cancer, thereby increasing the utility of unstructured medical big data.

Keywords