Chronic Diseases and Translational Medicine (Mar 2019)
Current advances in Hodgkin’s lymphoma
Abstract
Hodgkin’s lymphoma is a highly treatable malignancy. It has high cure rates yet there are many patients who relapse or are refractory to treatment. Traditionally, treatment has been with conventional chemotherapy; however, the development of brentuximab vedotin and immune checkpoint inhibitors has revolutionized the care of Hodgkin’s lymphoma. This is a review of the current advances in the management of Hodgkin’s lymphoma and a review of ongoing clinical trials in the field. Keywords: Hodgkin’s lymphoma, Brentuximab vedotin, Nivolumab, Pembrolizumab, Doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD)