Malignant Peripheral Nerve Sheath Tumor - A Case Report

Abstract

Malignant Peripheral Nerve Sheath Tumor [MPNST] is an extremely rare tumor affecting the oral cavity. It refers to sarcomas that arise from nerve or display features of neural differentiation. Here we present a case of 30-year old male patient with MPNST of right side of the mandible. There was a family history of neurotibromatosis in this case. Histologically, pleomorphic spindle cells with wavy nuclei, light stained cytoplasm, and mitotic activity were observed. The clinical presentation, radiological findings, and light microscopic findings are described in detail. The criteria for diagnosing these tumors and recent advances for diagnosis have also been highlighted.

Keywords

• Malignant Peripheral Nerve Sheath Tumor (MPNST)
• neurofibromatosis
• mandible. Malignant Peripheral Nerve Sheath Tumor (MPNST)
• neurofibromatosis
• mandible