Does current ovarian endometrioma increase the time for DOR patients to reach live birth in IVF?

Abstract

Abstract Background The contents of ovarian endometrioma (OMA) such as inflammatory mediators, reactive oxygen species, and iron may disrupt normal folliculogenesis and result in subsequent oocyte apoptosis. Therefore, women with OMA have a potential risk of diminished ovarian reserve (DOR). The purpose of this study is to compare the in vitro fertilization (IVF) outcomes and efficiency between DOR patients with and without current OMA. Methods This retrospective case-control study included a total of 493 women with DOR (serum anti-Müllerian hormone level 0.05). Total time to achieve live birth has no statistically significant difference between Group A1 and Group B1 (P > 0.05). Conclusion For DOR women, presence of endometrioma did not affect the IVF outcomes. Even the time to get live birth was not prolonged by current OMA.

Keywords

• Ovarian endometriomas
• Diminished ovarian reserve
• In vitro fertilization
• Cumulative live birth rate
• Time to achieve live birth