Nature Communications (Jan 2023)

Sensory nerve niche regulates mesenchymal stem cell homeostasis via FGF/mTOR/autophagy axis

  • Fei Pei,
  • Li Ma,
  • Junjun Jing,
  • Jifan Feng,
  • Yuan Yuan,
  • Tingwei Guo,
  • Xia Han,
  • Thach-Vu Ho,
  • Jie Lei,
  • Jinzhi He,
  • Mingyi Zhang,
  • Jian-Fu Chen,
  • Yang Chai

DOI
https://doi.org/10.1038/s41467-023-35977-4
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 18

Abstract

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Sensory nerves are important for tissue homeostasis. Here the authors show that sensory nerves contribute to Mesenchymal stem cell maintenance via FGF1, mTOR signaling and autophagy.