Hematology, Transfusion and Cell Therapy (Nov 2021)
BONE AS A SITE OF EXTRAMEDULLARY DISEASE IN ACUTE LYMPHOBLASTIC LEUKEMIA
Abstract
Case report: We describe 3 children with pre B acute lymphoblastic leukemia (ALL).The first two were evaluated in orthopedic clinics because of limping due to ischium involvement and bone fracture suspicion due to involvement of upper limb bones.As a result of normal hemograms in both cases, leukemia diagnosis delayed.The third patient experienced bone marrow and vertebral column relapse of ALL presenting with nuchal rigidity mimicking meningitis.Bone should be considered as a site of extramedullary disease.