INDEXES OF HUMORAL IMMUNITY IN PATIENTS WITH BRUCELLOSIS

Abstract

Serum immunoglobulin A, M, G сontents, specific antibodies and circulating immune complexes were studied in 278 patients with acute, subacute and chronic brucellosis (resp., 84, 98 and 96 cases). Significantly increased levels of serum immunoglobulins, specific antibodies and circulating immune complexes are found in various clinical forms of brucellosis. Serum contents of IgA, M, G and circulating immune complexes did not depend on clinical stage of brucellosis. Higher levels of specific antibodies, as determined by agglutination and hemagglutination reactions, were detected in acute and sub-acute brucellosis.

Keywords

• brucellosis
• immunoglobulins
• antibodies
• immune complexes