Inhibition of DNA Methylation at the MLH1 Promoter Region Using Pyrrole–Imidazole Polyamide

• Ken-ichi Shinohara,
• Natsumi Yoda,
• Kiyoko Takane,
• Takayoshi Watanabe,
• Masaki Fukuyo,
• Kyoko Fujiwara,
• Kazuko Kita,
• Hiroki Nagase,
• Tetsuhiro Nemoto,
• Atsushi Kaneda

Affiliations

Ken-ichi Shinohara

†Department of Molecular Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan

Natsumi Yoda

†Department of Molecular Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan

Kiyoko Takane

†Department of Molecular Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan

Takayoshi Watanabe

Laboratory of Cancer Genetics, Chiba Cancer Center Research Institute, Chiba, Japan

Masaki Fukuyo

†Department of Molecular Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan

Kyoko Fujiwara

Innovative Therapy Research Group, Nihon University Research Institute of Medical Science, Nihon University School of Medicine, Tokyo, Japan

Kazuko Kita

†Department of Molecular Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan

Hiroki Nagase

Laboratory of Cancer Genetics, Chiba Cancer Center Research Institute, Chiba, Japan

Tetsuhiro Nemoto

⊥Department of Pharmaceutical Chemistry, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan

Atsushi Kaneda

†Department of Molecular Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan