Regulation at a distance of biomolecular interactions using a DNA origami nanoactuator

Yonggang Ke; Travis Meyer; William M. Shih; Gaetan Bellot

doi:10.1038/ncomms10935

Nature Communications (Mar 2016)

Regulation at a distance of biomolecular interactions using a DNA origami nanoactuator

Yonggang Ke,
Travis Meyer,
William M. Shih,
Gaetan Bellot

Affiliations

Yonggang Ke: Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University
Travis Meyer: Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University
William M. Shih: Wyss Institute for Biologically Inspired Engineering, Harvard University
Gaetan Bellot: Department of Neuroscience, Institut de Génomique Fonctionnelle, Centre National de la Recherche Scientifique, CNRS Unité Mixte de Recherche UMR 5203, Institut National de la Santé et de la Recherche Médicale, INSERM U1191, 141 rue de la Cardonille, F-34000 Montpellier, France

DOI: https://doi.org/10.1038/ncomms10935
Journal volume & issue: Vol. 7, no. 1
pp. 1 – 8

Abstract

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The construction of nano-machines requires building nano-scale structures with controllable functions. Here the authors use DNA origami to construct an allosteric actuator which can act as signal propagator and an environmental sensor.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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