Hypersensitivity pneumonitis with Paecilomyces as suspected inciting antigen

Masayuki Watanabe; Ryo Okuda; Yuriko Ishida; Shinobu Sagawa; Tatsuya Muraoka; Satoshi Ikeda; Tomoe Sawazumi; Tamiko Takemura; Eri Hagiwara; Takashi Ogura

Respiratory Medicine Case Reports (Jan 2024)

Hypersensitivity pneumonitis with Paecilomyces as suspected inciting antigen

Masayuki Watanabe,
Ryo Okuda,
Yuriko Ishida,
Shinobu Sagawa,
Tatsuya Muraoka,
Satoshi Ikeda,
Tomoe Sawazumi,
Tamiko Takemura,
Eri Hagiwara,
Takashi Ogura

Affiliations

Masayuki Watanabe: Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan; Corresponding author. Departments of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, 6-16-1 Tomioka-higashi, Kanazawa-ku, Yokohama, Japan.
Ryo Okuda: Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan
Yuriko Ishida: Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan
Shinobu Sagawa: Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan
Tatsuya Muraoka: Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan
Satoshi Ikeda: Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan
Tomoe Sawazumi: Department of Pathology, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan
Tamiko Takemura: Department of Pathology, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan
Eri Hagiwara: Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan
Takashi Ogura: Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan

Journal volume & issue: Vol. 49
p. 102013

Abstract

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A 73-year-old man visited our hospital for persistent cough. Chest high-resolution CT (HRCT) showed infiltration shadows in lower lobes and diffuse ground glass opacities in the upper lobes. Blood tests showed elevated white blood cell, C-reactive protein, surfactant protein D, and Krebs von den Lungen-6 levels. After an antigen avoidance test, his HRCT and blood test findings improved; we diagnosed him with hypersensitivity pneumonitis (HP). A culture of the rotting interior walls within his home revealed Paecilomyces, which we believe caused his HP. Given the few patients with Paecilomyces-induced HP, systematic approach was important to identify the inciting antigen.

Published in Respiratory Medicine Case Reports

ISSN: 2213-0071 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the respiratory system
Website: http://www.journals.elsevier.com/respiratory-medicine-case-reports/

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