PLoS ONE (Jan 2021)

Clinical significance of hypoalbuminemia in patients with scrub typhus complicated by acute kidney injury.

  • Ju Hwan Oh,
  • Ji Hye Lim,
  • A Young Cho,
  • Kwang Young Lee,
  • In O Sun

DOI
https://doi.org/10.1371/journal.pone.0247584
Journal volume & issue
Vol. 16, no. 2
p. e0247584

Abstract

Read online

BackgroundThis study aimed to investigate the clinical significance of hypoalbuminemia (HA) in patients with scrub typhus complicated by acute kidney injury (AKI).MethodsFrom 2009 to 2018, 611 patients were diagnosed with scrub typhus. We divided the patients into two groups [normoalbuminemia (NA) vs. HA] based on the serum albumin level of 3.0 g/dL and compared the incidence, clinical characteristics, and severity of AKI based on the RIFLE classification between the two groups.ResultsOf the total 611 patients, 78 (12.8%) were categorized into the HA group. Compared to patients in the NA group, patients in the HA group were older (73 ± 9 vs. 62 ± 14 years, PConclusionSerum albumin level is helpful to predict the development and severity of scrub typhus-associated AKI.