Dose-Response (Oct 2011)

Radiation Worker Protection by Exposure Scheduling

  • Richard Blankenbecler

DOI
https://doi.org/10.2203/dose-response.11-029.blankenbecler
Journal volume & issue
Vol. 9

Abstract

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The discovery of the protective adaptive response of cells to a low dose of radiation suggests applications to radiation worker/first responder protection. Its use in cancer radiotherapy has been discussed in a separate publication. This paper describes simple changes in scheduling that can make use of these beneficial adaptive effects for protection. No increase in total exposure is necessary, only a simple change in the timing of radiation exposure. A low dose of radiation at a sufficient dose rate will trigger the adaptive response. This in turn will offer a considerable protection against the damage from a subsequent high dose. A simple scenario is discussed as well as a brief review of the experimental basis of the adaptive response.