Infection and Drug Resistance (Jun 2025)
Stenotrophomonas Maltophilia Necrotizing Soft Tissue Infection in an Acute Myeloid Leukemia Patient
Abstract
Hao Xu,1 Youhai Xu,1 Hesheng He,1 Dexi Huang,2 Guiping Su,1 Dongping Huang1 1Department of Hematology, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, People’s Republic of China; 2Department of Laboratory Medicine, Tongling City Hospital, Tongling, People’s Republic of ChinaCorrespondence: Dongping Huang, Department of Hematology, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, West Zheshan Road 2, Wuhu, 241000, People’s Republic of China, Tel/Fax +86-0553-5739176, Email [email protected] Guiping Su, Department of Hematology, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, West Zheshan Road 2, Wuhu, 241000, People’s Republic of China, Tel/Fax +86-0553-5739176, Email [email protected]: We present a case of Stenotrophomonas maltophilia-induced soft tissue infection in a patient with acute myeloid leukemia (AML), who exhibited atypical symptoms and lab findings. The patient fully recovered following ultrasound-guided drainage and appropriate medical intervention. Due to Stenotrophomonas maltophilia’s multi-drug resistance and high mortality rate, we share this case to highlight the importance of timely diagnosis and treatment for this aggressive infection in immunocompromised individuals.Keywords: acute myeloid leukaemias, stenotrophomonas maltophilia, drug resistance