INTERIGIONAL VARIABILITY OF THE HUMAN SELENIUM STATUS

Abstract

Aim of the present work was evaluation of factors affecting interregional variability of the human selenium status.Discussion. Essentiality of selenium to human beings determines the priority of the selenium status evaluation in different regions of the world. At the same time interregional variability of the human selenium status biomarkers are often underestimated. Among factors affecting the human selenium status geochemical characteristic of soils and anthropogenic influence are proved to be the most significant. The importance of seas and oceans are emphasized as important sources of the element. Examples of great interregional variability of the human selenium status are indicated and the importance of complex approach for evaluation of ecological risks connected with inadequate selenium consumption are emphasized. Such an approach should combine the data of selenium distribution in soils, levels of selenium bio concentration by different plants species, selenium content in water, food products and in human biological fluids and tissues. Difficulties in the human selenium status optimization are shown to be typical in regions with significant geochemical variations and intensive anthropogenic loading.Conclusions. High interregional variability of the human selenium status determines the necessity of complex approach in revealing ecological risks connected with selenium deficiency of excess in the environment both in regions with high utilization of local food products and in large industrial regions and towns and also in conditions of separate specific industrial production.

Keywords

• the human selenium status
• inter regional variability
• geochemical and anthropogenic factors