370 Pharmacodynamic assessment of a novel FAP-targeted 4–1BB agonist, administered as single agent and in combination with atezolizumab to patients with advanced solid tumors

• Josep Tabernero,
• Maurizio Ceppi,
• Victor Moreno,
• Michael Hettich,
• Miguel Sanmamed,
• Christina Claus,
• Tatiana Hernandez,
• Iben Spanggaard,
• Analia Azaro,
• Maria Martinez Garcia,
• Alejo Rodriguez-Vida,
• Florian Heil,
• Oliver Krieter,
• Oliver Grimm,
• Marta Canamero,
• Jose Duarte,
• Alexandra-Cristina Nica,
• Iakov Davydov,
• Chia-Huey Ooi,
• Christian Heichinger,
• Ernesto Guarin,
• Radoiane Helbaj,
• Tamara Tanos,
• Eveline Nueesch,
• Irene Moreno

Affiliations

Josep Tabernero

95Medical Oncology Department, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain

Maurizio Ceppi

6Roche pRED, Zürich, Switzerland

Victor Moreno

Unit of Biomarkers and Susceptibility, Oncology Data Analytics Program (ODAP), Catalan Institute of Oncology (ICO), Oncobell Program, Bellvitge Biomedical Research Institute (IDIBELL) and CIBERESP, L'Hospitalet de Llobregat, Barcelona, Spain

Michael Hettich

Aff1 grid.5963.9Department of Radiation OncologyMedical Center, Faculty of Medicine, University of Freiburg Freiburg Germany

Miguel Sanmamed

Aff1 grid.47100.320000000419368710Yale University New Haven CT USA

Christina Claus

Roche Innovation Center Zurich, Schlieren, Switzerland

Tatiana Hernandez

1Hospital Fundación Jiménez Díaz, Madrid, Spain

Iben Spanggaard

3Rigshospitalet University Hospital, Copenhagen, Denmark

Analia Azaro

4Vall d’Hebron University Hospital, Barcelona, Spain

Maria Martinez Garcia

5Hospital del Mar-CIBERONC, Barcelona, Spain

Alejo Rodriguez-Vida

5Hospital del Mar-CIBERONC, Barcelona, Spain

Florian Heil

6Roche pRED, Zürich, Switzerland

Oliver Krieter

6Roche pRED, Zürich, Switzerland

Oliver Grimm

6Roche pRED, Zürich, Switzerland

Marta Canamero

6Roche pRED, Zürich, Switzerland

Jose Duarte

6Roche pRED, Zürich, Switzerland

Alexandra-Cristina Nica

6Roche pRED, Zürich, Switzerland

Iakov Davydov

6Roche pRED, Zürich, Switzerland

Chia-Huey Ooi

6Roche pRED, Zürich, Switzerland

Christian Heichinger

6Roche pRED, Zürich, Switzerland

Ernesto Guarin

6Roche pRED, Zürich, Switzerland

Radoiane Helbaj

6Roche pRED, Zürich, Switzerland

Tamara Tanos

6Roche pRED, Zürich, Switzerland

Eveline Nueesch

6Roche pRED, Zürich, Switzerland

Irene Moreno

7Centro Integral Oncológico Clara Campal, Madrid, Spain