A network of mixed actin polarity in the leading edge of spreading cells

Affiliations

Wen-Lu Chung: Department of Biochemistry, University of Zurich
Matthias Eibauer: Department of Biochemistry, University of Zurich
Wenhong Li: Department of Immunology, and Regenerative Biology, Weizmann Institute of Science
Rajaa Boujemaa-Paterski: Department of Biochemistry, University of Zurich
Benjamin Geiger: Department of Immunology, and Regenerative Biology, Weizmann Institute of Science
Ohad Medalia: Department of Biochemistry, University of Zurich

Abstract

Cryo-electron tomography reveals structural insights into F-actin assembly and dynamic reorganization in the leading edge of spreading cells.