The Polar
<i>Legionella</i>
Icm/Dot T4SS Establishes Distinct Contact Sites with the Pathogen Vacuole Membrane

Désirée Böck; Dario Hüsler; Bernhard Steiner; João M. Medeiros; Amanda Welin; Katarzyna A. Radomska; Wolf-Dietrich Hardt; Martin Pilhofer; Hubert Hilbi

doi:10.1128/mBio.02180-21

mBio (Oct 2021)

The Polar <i>Legionella</i> Icm/Dot T4SS Establishes Distinct Contact Sites with the Pathogen Vacuole Membrane

Désirée Böck,
Dario Hüsler,
Bernhard Steiner,
João M. Medeiros,
Amanda Welin,
Katarzyna A. Radomska,
Wolf-Dietrich Hardt,
Martin Pilhofer,
Hubert Hilbi

Affiliations

Désirée Böck: Institute of Molecular Biology and Biophysics, Department of Biology, ETH Zürich, Zürich, Switzerland
Dario Hüsler: Institute of Medical Microbiology, Faculty of Medicine, University of Zürich, Zürich, Switzerland
Bernhard Steiner: Institute of Medical Microbiology, Faculty of Medicine, University of Zürich, Zürich, Switzerland
João M. Medeiros: Institute of Molecular Biology and Biophysics, Department of Biology, ETH Zürich, Zürich, Switzerland
Amanda Welin: Institute of Medical Microbiology, Faculty of Medicine, University of Zürich, Zürich, Switzerland
Katarzyna A. Radomska: Institute of Molecular Biology and Biophysics, Department of Biology, ETH Zürich, Zürich, Switzerland
Wolf-Dietrich Hardt: Institute of Microbiology, Department of Biology, ETH Zürich, Zürich, Switzerland
Martin Pilhofer: Institute of Molecular Biology and Biophysics, Department of Biology, ETH Zürich, Zürich, Switzerland
Hubert Hilbi: ORCiD; Institute of Medical Microbiology, Faculty of Medicine, University of Zürich, Zürich, Switzerland

DOI: https://doi.org/10.1128/mBio.02180-21
Journal volume & issue: Vol. 12, no. 5

Abstract

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Legionnaires’ disease is a life-threatening pneumonia, which is characterized by high fever, coughing, shortness of breath, muscle pains, and headaches. The disease is caused by the amoeba-resistant bacterium L. pneumophila

Published in mBio

ISSN: 2161-2129 (Print); 2150-7511 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/mbio

About the journal