Multispectral optoacoustic imaging of dynamic redox correlation and pathophysiological progression utilizing upconversion nanoprobes

Xiangzhao Ai; Zhimin Wang; Haolun Cheong; Yong Wang; Ruochong Zhang; Jun Lin; Yuanjin Zheng; Mingyuan Gao; Bengang Xing

doi:10.1038/s41467-019-09001-7

Nature Communications (Mar 2019)

Multispectral optoacoustic imaging of dynamic redox correlation and pathophysiological progression utilizing upconversion nanoprobes

Xiangzhao Ai,
Zhimin Wang,
Haolun Cheong,
Yong Wang,
Ruochong Zhang,
Jun Lin,
Yuanjin Zheng,
Mingyuan Gao,
Bengang Xing

Affiliations

Xiangzhao Ai: Sino-Singapore International Joint Research Institute (SSIJRI)
Zhimin Wang: Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University
Haolun Cheong: Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University
Yong Wang: State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University
Ruochong Zhang: School of Electrical and Electronic Engineering, Nanyang Technological University
Jun Lin: State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences
Yuanjin Zheng: School of Electrical and Electronic Engineering, Nanyang Technological University
Mingyuan Gao: State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University
Bengang Xing: Sino-Singapore International Joint Research Institute (SSIJRI)

DOI: https://doi.org/10.1038/s41467-019-09001-7
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 11

Abstract

Read online

Reactive oxygen (ROS) and nitrogen (RNS) species are involved in key physiological processes and their balance is altered in various human diseases. Here the authors develop near-infrared upconversion nanoprobes to screen ROS/RNS dynamics simultaneously by multispectral optoacoustic imaging in vivo.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal