A Perspective on the Enhancer Dependent Bacterial RNA Polymerase

Abstract

Here we review recent findings and offer a perspective on how the major variant RNA polymerase of bacteria, which contains the sigma54 factor, functions for regulated gene expression. We consider what gaps exist in our understanding of its genetic, biochemical and biophysical functioning and how they might be addressed.

Keywords

• RNA polymerase
• Sigma54
• transcription
• AAA+ ATPase