The impact of supplementation with highland barley in different nutrients on weight loss: The nutrients and function relationship

Fan Xie; Yuting Yan; Xin Gao; Haocheng She; Jingyi Wang; Jie Li; Yi Zhang; Jun Zhang; Zhou Zhang; Lianzhong Ai

doi:10.1016/j.fochx.2025.102417

Food Chemistry: X (Apr 2025)

The impact of supplementation with highland barley in different nutrients on weight loss: The nutrients and function relationship

Fan Xie,
Yuting Yan,
Xin Gao,
Haocheng She,
Jingyi Wang,
Jie Li,
Yi Zhang,
Jun Zhang,
Zhou Zhang,
Lianzhong Ai

Affiliations

Fan Xie: Shanghai Engineering Research Center of Food Microbiology, School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China
Yuting Yan: Shanghai Engineering Research Center of Food Microbiology, School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China
Xin Gao: Shanghai Engineering Research Center of Food Microbiology, School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China
Haocheng She: Shanghai Engineering Research Center of Food Microbiology, School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China
Jingyi Wang: Shanghai Engineering Research Center of Food Microbiology, School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China
Jie Li: Shanghai Engineering Research Center of Food Microbiology, School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China
Yi Zhang: Crop Breeding & Cultivation Research Institute, Shanghai Academy of Agricultural Sciences, Shanghai 201403, China
Jun Zhang: Shidong Hospital, Yangpu Destrict, Shanghai 200438, China
Zhou Zhang: Shidong Hospital, Yangpu Destrict, Shanghai 200438, China; Correspondence author.
Lianzhong Ai: Shanghai Engineering Research Center of Food Microbiology, School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China; Correspondence author.

DOI: https://doi.org/10.1016/j.fochx.2025.102417
Journal volume & issue: Vol. 27
p. 102417

Abstract

Read online

The dietary fiber in highland barley (HB) may be a key nutrient in exerting its physiological functions. How about the effects of other nutrients? In this study, a high-fat diet (HFD)-induced obese mice was constructed to investigate the effects of HB in different nutrients on weight loss. The results showed that peeling treatment had varying effects on HB nutrients. Consumption of HB significantly mitigated weight gain, postprandial blood glucose levels, organ weight, adipose tissue weight, and fat accumulation in obese mice. Consumption of HB also ameliorated hepatic steatosis, hyperlipemia, abnormal liver function, and dysregulation of inflammatory factor expression in mice. Unpeeled and once peeled HB presented the best effect. Furthermore, HB consumption improved the imbalance of gut microbiota in HFD-induced mice, with protein and dietary fiber being the key factors in exerting the improvement effect. This study highlights the potential of protein and dietary fiber in HB for treating obesity.

Published in Food Chemistry: X

ISSN: 2590-1575 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Technology: Home economics: Nutrition. Foods and food supply; Technology: Chemical technology: Food processing and manufacture
Website: https://www.journals.elsevier.com/food-chemistry-x

About the journal

Abstract

Keywords