Эпилепсия и пароксизмальные состояния (Sep 2016)

EXPERIENCE OF TREATMENT OF DIFFERENT FORMS OF EPILEPSY WITH GENERIC TOPIRAMATE (The results of focus observation in out-patientclinics network of Moscow city public healthcare services)

  • O. L. Badalyan,
  • M. A. Bogomazova,
  • I. I. Zhuravleva,
  • A. M. Ismailov,
  • E. G. Komelkova,
  • L. N. Lesinker,
  • Yu. I. Logvinov,
  • O. V. Otcheskaya,
  • S. V. Petrov,
  • Yu. V. Solomatin,
  • A. М. Teplysheva,
  • T. N. Udovuchenko,
  • E. A. Khromykh,
  • A. S. Chukanova,
  • A. V. Lebedeva,
  • S. G. Burd,
  • A. N. Boiko,

Journal volume & issue
Vol. 4, no. 4
pp. 6 – 10

Abstract

Read online

Current work is dedicated to analysis of treatment with generic topiramate in mono- as well as in polytherapy in patients with different forms of epilepsy. Forclinical assessmentsHospital Anxiety and Depression Scale (HADS), quality of life questionnaire for patients with epilepsy (QOLIE-10) and efficacy primary assessment based on decrease in frequency of seizures and adverse events before and after switching to generic topiramate were used. As a result of focus investigation switch to Topsaver was associated with maintenance of stable therapeutic effect in more, than 80% of cases. No negative dynamics in changes of HADS and QOLIE-10 points were observed.

Keywords