The gut commensal fungus, Candida parapsilosis, promotes high fat-diet induced obesity in mice

Shanshan Sun; Li Sun; Kai Wang; Shanshan Qiao; Xinyue Zhao; Xiaomin Hu; Wei Chen; Shuyang Zhang; Hantian Li; Huanqin Dai; Hongwei Liu

doi:10.1038/s42003-021-02753-3

Communications Biology (Oct 2021)

The gut commensal fungus, Candida parapsilosis, promotes high fat-diet induced obesity in mice

Shanshan Sun,
Li Sun,
Kai Wang,
Shanshan Qiao,
Xinyue Zhao,
Xiaomin Hu,
Wei Chen,
Shuyang Zhang,
Hantian Li,
Huanqin Dai,
Hongwei Liu

Affiliations

Shanshan Sun: State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences
Li Sun: State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences
Kai Wang: State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences
Shanshan Qiao: State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences
Xinyue Zhao: Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College
Xiaomin Hu: Department of Medical Research Center, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College
Wei Chen: Department of Clinical Nutrition, Dept. of Health Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Shuyang Zhang: Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College
Hantian Li: State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences
Huanqin Dai: State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences
Hongwei Liu: State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences

DOI: https://doi.org/10.1038/s42003-021-02753-3
Journal volume & issue: Vol. 4, no. 1
pp. 1 – 11

Abstract

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Shanshan Sun, Li Sun, Kai Wang, et al. report that the gut commensal Candida parapsilosis is a causative fungus for the development of high fat-diet induced obesity in mice. Their results suggest that fungi could represent possible targets for combating obesity.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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