Biomedicines (Mar 2023)

Plant-Derived Exosome-like Nanoparticles for Biomedical Applications and Regenerative Therapy

  • Andari Sarasati,
  • Muhammad Hidayat Syahruddin,
  • Archadian Nuryanti,
  • Ika Dewi Ana,
  • Anggraini Barlian,
  • Christofora Hanny Wijaya,
  • Diah Ratnadewi,
  • Triati Dewi Kencana Wungu,
  • Hiroshi Takemori

DOI
https://doi.org/10.3390/biomedicines11041053
Journal volume & issue
Vol. 11, no. 4
p. 1053

Abstract

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Plant-derived exosome-like nanoparticles (PDENs) comprise various bioactive biomolecules. As an alternative cell-free therapeutic approach, they have the potential to deliver nano-bioactive compounds to the human body, and thus lead to various anti-inflammatory, antioxidant, and anti-tumor benefits. Moreover, it is known that Indonesia is one of the herbal centers of the world, with an abundance of unexplored sources of PDENs. This encouraged further research in biomedical science to develop natural richness in plants as a source for human welfare. This study aims to verify the potential of PDENs for biomedical purposes, especially for regenerative therapy applications, by collecting and analyzing data from the latest relevant research and developments.

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