FSH Beyond Fertility

Daria Lizneva; Alina Rahimova; Se-Min Kim; Ihor Atabiekov; Seher Javaid; Bateel Alamoush; Charit Taneja; Ayesha Khan; Li Sun; Ricardo Azziz; Tony Yuen; Mone Zaidi

doi:10.3389/fendo.2019.00136

Frontiers in Endocrinology (Mar 2019)

FSH Beyond Fertility

Daria Lizneva,
Alina Rahimova,
Se-Min Kim,
Ihor Atabiekov,
Seher Javaid,
Bateel Alamoush,
Charit Taneja,
Ayesha Khan,
Li Sun,
Ricardo Azziz,
Tony Yuen,
Mone Zaidi

Affiliations

Daria Lizneva: The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States
Alina Rahimova: The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States
Se-Min Kim: The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States
Ihor Atabiekov: The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States
Seher Javaid: The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States
Bateel Alamoush: The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States
Charit Taneja: The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States
Ayesha Khan: The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States
Li Sun: The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States
Ricardo Azziz: Academic Health and Hospital Affairs, State University of New York, Albany, NY, United States
Tony Yuen: The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States
Mone Zaidi: The Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States

DOI: https://doi.org/10.3389/fendo.2019.00136
Journal volume & issue: Vol. 10

Abstract

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The traditional view of follicle-stimulating hormone (FSH) as a reproductive hormone is changing. It has been shown that FSH receptors (FSHRs) are expressed in various extra-gonadal tissues and mediate the biological effects of FSH at those sites. Molecular, animal, epidemiologic, and clinical data suggest that elevated serum FSH may play a significant role in the evolution of bone loss and obesity, as well as contributing to cardiovascular and cancer risk. This review summarizes recent data on FSH action beyond reproduction.

Published in Frontiers in Endocrinology

ISSN: 1664-2392 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the endocrine glands. Clinical endocrinology
Website: https://www.frontiersin.org/journals/endocrinology

About the journal

Abstract

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