BMC Ophthalmology (Jul 2017)

Congenital aniridia with cataract: case series

  • Jin Da Wang,
  • Jing Shang Zhang,
  • Ying Xiong,
  • Jing Li,
  • Xiao Xia Li,
  • Xue Liu,
  • Jing Zhao,
  • Frank F. Tsai,
  • Jhanji Vishal,
  • Qi Sheng You,
  • Yao Huang,
  • Xiu Hua Wan

DOI
https://doi.org/10.1186/s12886-017-0503-6
Journal volume & issue
Vol. 17, no. 1
pp. 1 – 5

Abstract

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Abstract Background This study evaluates patients with congenital aniridia and cataract who underwent phacoemulsification, capsular tension ring placement, and foldable intraocular lens implantation. Methods In this prospective case series, 10 patients (17 eyes) underwent cataract surgery via a 3.2 mm clear corneal incision. A continuous circular capsulorhexis with <6 mm diameter was employed. A capsular tension ring and HOYA yellow foldable posterior chamber intraocular lens was implanted. All patients wore color contact lenses postoperatively. Paired t test was used to compare visual acuity, intraocular pressure, and corneal endothelial changes before and after surgery. Results A single surgeon performed all surgeries. The best-corrected visual acuity improved from value 1.03 ± 0.27LogMAR preoperatively to value 0.78 ± 0.26LogMAR postoperatively (p = 0.000). The photophobic symptoms improved significantly after surgery. The mean corneal endothelial cell density before and after surgery was 3280 ± 473 cells/mm2 and 2669 ± 850 cells/mm2, respectively (p = 0.006). None of the patients developed corneal endothelial decompensation or secondary glaucoma after surgery. Conclusions Treatment of congenital aniridia and coexistent cataract by phacoemulsification, posterior chamber foldable lens implantation, capsular tension ring placement was safe and effective. Use of colored contact lenses in the postoperative period can reduce photophobic symptoms in this group of patients. Trial registration ChiCTR-OOC-17011638 (retrospectively registered at 12,June,2017)

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