TESTOSTERONE AS A TOOL OF METABOLIC CONTROL OF MEN’S HEALTH (REVIEW)

Abstract

Nowadays late-onset hypogonadism in men is considered as one of the risk factors of cardiovascular diseases as well as obesity and type 2 diabetes. The pathogenetic mechanisms of testosterone metabolic effects on carbohydrate and lipid metabolism, the current data about the role of the imbalance of proinflammatory cytokines - interleukin-6 (IL-6), tumor necrosis factor alpha (TNFα), C-reactive protein (CRP) in the pathogenesis of metabolic disorders and late-onset hypogonadism in men considered in this review.

Keywords

• testosterone, obesity, metabolic syndrome, type 2 diabetes mellitus, late-onset hypogonadism