Archivio Italiano di Urologia e Andrologia (Feb 2024)

Iron homeostasis alterations and erectile dysfunction: A new issue in erectile disfunction treatment?

  • Claudio Marino,
  • Salvatore Iaconis,
  • Francesco Di Bello,
  • Gianluigi Cacace,
  • Giovanni Fusco,
  • Lorenzo Romano,
  • Ernesto Di Mauro,
  • Luigi Cirillo,
  • Vincenzo Maria Altieri,
  • Francesco Mastrangelo,
  • Luigi Napolitano,
  • Alessandro Palmieri

DOI
https://doi.org/10.4081/aiua.2024.12245

Abstract

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To the Editor, Erectile dysfunction (ED) is one of the most prevalent conditions affecting men globally, with significant psychological and social consequences. The prevalence varies across different populations, and it is estimated around 50% in men aged between 40 to 70. The etiology of ED is multifactorial, involving a complex crosstalk between psychological, hormonal, neurogenic, vascular, and structural factors. Recently, the role of iron homeostasis (IH) is emerging. [...]

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