HIRAYAMA DISEASE. CLINICAL CASE AND A REVIEW OF LITERATURE

Abstract

Hirayama disease is a rare neurological disease with unilateral or asymmetric bilateral distal upper limb paresis and muscle atrophy. Here the authors report a clinical case of patient with weakness of cluster muscles and distal asymmetric upper paraparesis. Taking into consideration complaints, clinical presentation and performed follow-up examination (bloodwork, cervical MRI in neutral position and with flexion, MRI of lower limb muscles and electroneuromyography) the patient was diagnosed with Hirayama disease with asymmetric upper extremities. Also, there is a review of literature with pathogenesis, clinical presentation, diagnostic and treatment approaches to this disease.

Keywords

• hirayama disease
• monomelic amyotrophy
• magnetic resonance tomography with flexion
• electroneuromyo-graphy