ACUTE CORONARY SYNDROME IN PATIENTS WITH DIABETES MELLITUS: ON THE WAY TO MUNICH-2008

Abstract

Results of trials on the therapy of patients with acute myocardial infarction (MI) and glucose metabolism disturbances are discussed. According to author’s data, 67% of patients with MI have glucose tolerance disturbances including 44% of patient with these reaching the level of diabetes mellitus (DM). Mortality risk in patients with MI and DM is some times higher than this in patients with MI without glucose metabolism disturbances. Active glucose correction results in significant mortality risk reduction. It is necessary to reduce glucose blood level to normal one as soon as possible in patients with MI and DM. It can be managed with insulin, if the glucose blood level is intensively increased or with per oral glucose lowering medicines, if there is moderate hyperglycemia. In spite of wide usage of these class drugs, it is not still clear which medicine is mostly effective in patients with MI and glucose metabolism disturbances.

Keywords

• acute myocardial infarction
• diabetes mellitus
• glucose metabolism disturbances