Clinical observation of flap-free LASEK combined mitomycin C and LASEK on the treatment of moderate and low myopia

Abstract

AIM: To compare the clinical effectivity of flap-free LASEK combined mitomycin C(MMC)and LASEK for moderate and low myopia, to assess the safety and effectiveness of flap-free LASEK combined MMC surgery.METHODS: Forty-four patients eighty-six eyes(-2.00- -7.00D)were divided randomly into two groups, group A and group B. Group A underwent flap-free LASEK combined MMC, group B underwent common LASEK. The uncorrected visual acuity(UCVA)scores were detected in 1 week,1 month, 3 months after surgery, the haze scores were detected in 1 week,10 days,1 month, 3,6 months after surgery. All subjective pain scores were evaluated in 1 day, 4 days, 7 days after the surgery. The days of corneal epithelium healing were recorded.RESULTS: The difference of the UCVA had no statistical significance in 1 week, 1 month, 3 months after surgery between the two groups. The difference of haze scores had no statistical significance in 1 week, 10 days, 3 months, 6 months after surgery between the two groups, but in 1 month, haze scores were significant difference in group A and B(χ2=5.185, Pχ2=10.135, Pχ2=38.78, Pχ2=34.624, PCONCLUSION: haze 0.5 degree was less and lighter in 1 month in flap-free LASEK surgery combined MMC than that in LASEK. Pain scores were lower in 1 day, 4 days in Flap-free LASEK surgery combined MMC than that in LASEK. There was no obviously difference in the days of corneal epithelium healing and UCVA between the two groups.

Keywords

• moderate and low myopia
• flap-free LASEK
• mitomycin C
• LASEK