Nature Communications (Oct 2020)
Genomic surveillance of COVID-19 cases in Beijing
- Pengcheng Du,
- Nan Ding,
- Jiarui Li,
- Fujie Zhang,
- Qi Wang,
- Zhihai Chen,
- Chuan Song,
- Kai Han,
- Wen Xie,
- Jingyuan Liu,
- Linghang Wang,
- Lirong Wei,
- Shanfang Ma,
- Mingxi Hua,
- Fengting Yu,
- Lin Wang,
- Wei Wang,
- Kang An,
- Jianjun Chen,
- Haizhou Liu,
- Guiju Gao,
- Sa Wang,
- Yanyi Huang,
- Angela R. Wu,
- Jianbin Wang,
- Di Liu,
- Hui Zeng,
- Chen Chen
Affiliations
- Pengcheng Du
- Beijing Ditan Hospital, Capital Medical University
- Nan Ding
- Beijing Ditan Hospital, Capital Medical University
- Jiarui Li
- Beijing Ditan Hospital, Capital Medical University
- Fujie Zhang
- Beijing Ditan Hospital, Capital Medical University
- Qi Wang
- Beijing Ditan Hospital, Capital Medical University
- Zhihai Chen
- Beijing Ditan Hospital, Capital Medical University
- Chuan Song
- Beijing Ditan Hospital, Capital Medical University
- Kai Han
- Beijing Ditan Hospital, Capital Medical University
- Wen Xie
- Beijing Ditan Hospital, Capital Medical University
- Jingyuan Liu
- Beijing Ditan Hospital, Capital Medical University
- Linghang Wang
- Beijing Ditan Hospital, Capital Medical University
- Lirong Wei
- Beijing Ditan Hospital, Capital Medical University
- Shanfang Ma
- Beijing Ditan Hospital, Capital Medical University
- Mingxi Hua
- Beijing Ditan Hospital, Capital Medical University
- Fengting Yu
- Beijing Ditan Hospital, Capital Medical University
- Lin Wang
- MGI, BGI-Shenzhen
- Wei Wang
- MGI, BGI-Shenzhen
- Kang An
- BGI-Genomics, BGI-Shenzhen
- Jianjun Chen
- CAS Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences
- Haizhou Liu
- National Virus Resource Center, Wuhan Institute of Virology, Chinese Academy of Sciences
- Guiju Gao
- Beijing Ditan Hospital, Capital Medical University
- Sa Wang
- Beijing Ditan Hospital, Capital Medical University
- Yanyi Huang
- Biomedical Pioneering Innovation Center (BIOPIC), Beijing Advanced Innovation Center for Genomics (ICG), College of Chemistry and Molecular Engineering, Peking-Tsinghua Center for Life Sciences, Peking University
- Angela R. Wu
- Division of Life Science and Department of Chemical and Biological Engineering, Hong Kong University of Science and Technology
- Jianbin Wang
- School of Life Sciences, Tsinghua-Peking Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology (ICSB), Chinese Institute for Brain Research (CIBR), Tsinghua University
- Di Liu
- CAS Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences
- Hui Zeng
- Beijing Ditan Hospital, Capital Medical University
- Chen Chen
- Beijing Ditan Hospital, Capital Medical University
- DOI
- https://doi.org/10.1038/s41467-020-19345-0
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 9
Abstract
In this study, Chen and colleagues present genomic sequences of 102 SARS-CoV-2 isolates collected in Beijing. They look closely at genomic variation between isolates that arose as a result of domestic and global transmission. Their data suggest that SARS-CoV-2 genomes have a high mutational tolerance, which may have potential implications for the development of vaccines.
