Research progress of pulpotomy and crown pulp regeneration

Abstract

Crown pulp regeneration is a method to replace the pulp-capping agent with stem cells and scaffold structures, which are placed on the section of healthy root pulp tissue after pulpotomy to regenerate the pulp-dentin complex in the crown. This paper reviews the significance, physiological basis, application and challenges of crown pulp regeneration to provide new ideas for the study of pulp regeneration. The results of a literature review show that the combination of traditional pulpotomy, stem cell biology and tissue engineering, as well as the regeneration of crowns and pulp by using the tissue repair potential of healthy root pulp can effectively promote the regeneration of dentin and parts of pulp. In recent years, with the development of research on pulp regeneration, many challenges have been gradually revealed. It is necessary not only to select the treatment methods that can promote the proliferation and differentiation of dental pulp stem cells safely and effectively but also to continue to explore the scaffold materials suitable for the structural and functional diversity of the pulp chamber.

Keywords

• pulpotomy，
• crown pulp regeneration，
• root pulp，
• pulp-capping agent，
• mineral trioxide aggregate，
• iroot bioceramics，
• pulp regeneration，
• dental pulp stem cell ，
• endodontic-dentin complex，
• hydrogels scaffold，