RUDN Journal of Medicine (Dec 2009)
Morphological changes of the mucous membrane of small intestines of the experimental animals at the chronic alcoholic intoxication
Abstract
The digestive path is subjected to ethanol influence at a chronic alcoholic intoxication. The influence of different terms of an alcoholic intoxication on morphological characteristics of small intestines has been investigated. In 2 months after the beginning of taking alcohol in the following indicators increased: fiber height, the volume of enterocyte kernels, specific quantity of mitoses in basal layer of mucous small intestines. In 6 months the decrease of mitotic sharing cages was observed, at the same time the volume of enterocyte kernels both in fiber and in crypta increased. Thus, there is a decrease in regenerative ability of small intestine, mucous membrane of a in a tandem with the increase of functional activity of this department of a digestive path.