Nature Communications (Jul 2018)

Bilophila wadsworthia aggravates high fat diet induced metabolic dysfunctions in mice

  • Jane M. Natividad,
  • Bruno Lamas,
  • Hang Phuong Pham,
  • Marie-Laure Michel,
  • Dominique Rainteau,
  • Chantal Bridonneau,
  • Gregory da Costa,
  • Johan van Hylckama Vlieg,
  • Bruno Sovran,
  • Celia Chamignon,
  • Julien Planchais,
  • Mathias L. Richard,
  • Philippe Langella,
  • Patrick Veiga,
  • Harry Sokol

DOI
https://doi.org/10.1038/s41467-018-05249-7
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 15

Abstract

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Lipid intake is known to promote Bilophila wadsworthia growth. Here the authors show that B. wadsworthia aggravates high fat diet induced metabolic dysfunctions and its suppression, both pharmacologically or mediated by Lactobacillus rhamnosus, limits the severity of metabolic impairment.