Dehydrogenative reagent-free annulation of alkenes with diols for the synthesis of saturated O-heterocycles

Abstract

Dehydrogenative annulation is a valuable approach to heterocycles, however, stoichiometric oxidants are often required. Here, the authors describe the electrochemical dehydrogenative annulation of diols and alkenes to generate dioxanes and dioxepanes under metal- and oxidant-free conditions.